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Genetic Predisposition to Cancer, An Issue of Hematology/Oncology Clinics of North America, 1st Edition

Authors :
Ken Offit & Mark Robson
Date of Publication: 12/2010
This issue serves as a timely review of both the genetic and genomic factors resulting in a predisposition to human cancer. There is now strong evidence to support the use of genetic testing for cancer predisposition in the practice of preventive me ...view more
This issue serves as a timely review of both the genetic and genomic factors resulting in a predisposition to human cancer. There is now strong evidence to support the use of genetic testing for cancer predisposition in the practice of preventive medicine, and at the same time, there is emerging new literature defining the role of genomic approaches to assessment of cancer predisposition. Articles address predisposition syndromes in the areas of breast cancer, lower GI cancer, genitourinary cancer, pediatric cancer, endocrine cancer, and hematologic malignancy.
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This issue serves as a timely review of both the genetic and genomic factors resulting in a predisposition to human cancer. There is now strong evidence to support the use of genetic testing for cancer predisposition in the practice of preventive medicine, and at the same time, there is emerging new literature defining the role of genomic approaches to assessment of cancer predisposition. Articles address predisposition syndromes in the areas of breast cancer, lower GI cancer, genitourinary cancer, pediatric cancer, endocrine cancer, and hematologic malignancy.

Author Information
By Ken Offit, MD, MPH and Mark Robson, MD